Delivery updates: Please note orders placed after Wednesday 22nd May may be delivered after the Spring Bank Holiday. 


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During the menopause, levels of female hormones, including oestrogen, start to fall. Evorel is a patch medication that contains the active ingredient oestradiol, a synthetic form of oestrogen. Using Evorel can therefore offset the symptoms of the menopause. Evorel is a form of hormone replacement therapy (HRT).

  • Oestrogen-only HRT medication
  • Treats menopausal symptoms
  • Easy-to-use patches
  • Genuine medication
  • Shipped from EU Pharmacies
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You will need to answer a few questions about your health before completing purchase of this item.

  • Evorel contains a synthetic version of oestrogen called oestradiol
  • Eumeds stocks Evorel in four different strengths
  • The patches can help to minimise symptoms of the menopause including hot flushes, night sweats and vaginal dryness
  • Evorel does not contain the other female sex hormone, progesterone, and so it may not suit all women
  • Some women may need to take a progesterone medication in addition to Evorel
  • It is important to read the patient leaflet for a full list of side effects and cautions.

Evorel contains oestradiol, a synthetic version of oestrogen. During the menopause, oestrogen levels fall, and using Evorel helps to restore the levels to treat side effects such as vaginal dryness, hot flushes, and night sweats. 

Evorel does not contain a drug that mimics progesterone, the other female sex hormone. Taking oestrogen alone can be dangerous for women who still have their uterus (womb), and so this group of women should also take a medication that contains progesterone.

Women who have had a hysterectomy (uterus removal) can use Evorel on its own.

An Evorel patch should be applied to the skin twice weekly. Each patch should therefore be changed every 3 or 4 days (alternating). You may choose to change your patch on a Monday and Thursday, for example.

If you no longer have periods, or your periods have become irregular, Evorel can be started at any time. If you still have regular menstrual cycles, you should start your first patch within 5 days of your period. 

If you already take a continuous combined HRT medication, you can start taking Evorel at any time. If you currently take a cyclic or sequential HRT treatment, you should start Evorel the day after you finish your current cycle.

Each patch should be applied to clean, dry skin of the lower abdomen, buttock, or thigh. It is best to avoid areas of the skin where the patch may be rubbed, such as the waistline area. When you replace the patch, apply it to a new area away from the location you have just used. 

The Evorel patch should remain in place during showering, bathing and exercise.

After removal, dispose of the patch carefully away from children.

You will be prescribed the lowest dose of Evorel to manage your symptoms. After one month, your doctor can reassess whether the dose has offset the symptoms of the menopause without causing side effects such as breast tenderness.

The following dose patches are available:

  • Evorel 25 releases 25 micrograms of oestradiol every 24 hours
  • Evorel 50 releases 50 micrograms of oestradiol every 24 hours
  • Evorel 75 releases 75 micrograms of oestradiol every 24 hours
  • Evorel 100 releases 100 micrograms of oestradiol every 24 hours.

Some women many be prescribed Evorel 50, 75 or 100 for prevention of osteoporosis, if other bone protection medications are not suitable.

Like all medications, Evorel can have some side effects. The most common side effects include:

  • Itching or a rash at the site of the patch
  • Low mood
  • Migraines or headaches
  • Dizziness
  • Abdominal pain
  • Diarrhoea
  • Nausea
  • Aches and pains
  • Breast pain
  • Irregular menstrual bleeding
  • Weight increase or decrease.

If these side effects persist, you should speak to your doctor for further advice as a lower dose of HRT may be required.

Using HRT can cause a slight increase in the risk of some cancers including breast and uterine cancer. The risk increases when using a higher strength preparation for a long period. It is important that the benefits of using Evorel outweigh the potential risks.

Serious allergic reactions happen very rarely. If you have a severe allergic reaction (anaphylaxis) including breathlessness, lip swelling or tongue swelling, call 999 immediately.

Evorel may not be suitable for everyone. You should tell your prescriber if you:

  • Have ever had breast cancer (or suspected breast cancer)
  • Have endometrial (or another oestrogen dependent) cancer
  • Have undiagnosed vaginal or genital bleeding
  • Have endometrial hyperplasia, fibroids, or endometriosis
  • Have, or have ever had, a PE (pulmonary embolism) or DVT (deep vein thrombosis) – a blood clot to the lungs or leg
  • Have a thrombophilic disorder (blood clotting disorders)
  • Have angina or have had a heart attack (myocardial infarction), or any other form of arterial blood clot
  • Have had a stroke
  • Have liver disease
  • Have porphyria
  • Have hypertension (high blood pressure)
  • Have diabetes
  • Have migraine
  • Have systemic lupus erythematosus (SLE or lupus)
  • Have epilepsy
  • Have asthma
  • Have otosclerosis.

If you become pregnant whilst taking Evorel, the patches must be stopped immediately. Evorel is not suitable for use when breastfeeding.

Some medications can interact with Evorel. You may be advised that Evorel will not suit you if you already take:

  • Phenytoin, phenobarbital, carbamazepine, or lamotrigine for seizures or fits
  • Ritonavir or nelfinavir
  • Rifampicin
  • Rifabutin
  • Nevirapine
  • Efavirenz
  • Bosentan
  • St John’s Wort (Hypericum Perforatum).

Because Evorel may not suit everyone, we will complete a Consultation with you including a health questionnaire. This will ensure that the medication will be suitable for you.

A qualified prescriber will review your current medications, including any herbal remedies or supplements, to ensure that Evorel will not interact with them. 

Once prescribed, Evorel will be ordered on your behalf via electronic prescription. Evorel will then be conveniently dispatched from one of our partner pharmacies.

Buy Evorel

Buying Evorel Online

Can I buy Evorel online?

You can safely buy Evorel online at EU Meds. You will first need to have an online consultation with a pharmacist independent prescriber before your order will be supplied. The online consultation will ensure that Evorel is the right medication for your medical condition.

Do I need a prescription for Evorel?

Yes, in order to purchase Evorel you will need a valid prescription. Please note, all requests for supply of prescription medications are subject to an online clinical consultation and the decision to prescribe will be made by a doctor.

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Our Customer Service is available Monday to Friday 9am - 4pm. If you need urgent assistance, do not use this service. Call 111, or in an emergency call 999. Visit our help section