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Priligy is a brand name for the prescription medication dapoxetine. It is prescribed to help manage the sexual health condition premature ejaculation (both short term PE and lifelong PE) and is taken 1 to 3 hours before you sexual activity. Successful treatment of premature ejaculation can help to improve the given sexual relationship of a patient suffering from PE. The most common side effects include dizziness or feeling faint.
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Summary of Priligy
|Type of drug||Selective serotonin reuptake inhibitors (SSRIs)|
|Health conditions prescribed for||Premature ejaculation (PE)|
|Active Ingredients||Dapoxetine hydrochloride|
|Available strengths||30mg, 60mg|
|Possible side effects||Dizziness, light headedness, nausea, vomiting, excessive sweating, confusion, headache|
|Patient Information Leaflet||For more information about this medication, see the Priligy patient information leaflet.|
What is Priligy?
Priligy for Premature Ejaculation
- Priligy contains the active ingredient dapoxetine
- Priligy pills are a prescription premature ejaculation treatment to facilitate delayed ejaculation
- Priligy is a sexual medicine that is only taken before you have sex, it is not a regular medication
- Common side effects include dizziness, feeling faint and nausea (feeling sick)
- It is important to read the patient leaflet for a full list of side effects and cautions.
Patient Information Leaflet
For more information on the prescription PE medication please refer to the Priligy patient information leaflet.
Video: An overview of Priligy
Take a look at the video below to get a simple overview of Priligy, including what it is used for, dosages, side effects and precautions:
How Does Priligy Work?
Premature ejaculation is a form of sexual dysfunction used to describe an orgasm in a man that occurs more quickly than he or his partner would like during sexual intercourse. Sometimes premature ejaculation during sexual activity can be related to stress or anxiety, and may resolve on its own. In other cases, men may require treatment with dapoxetine. Priligy has been designed to prolong the time it takes to ejaculate.
Priligy (dapoxetine) is a selective serotonin reuptake inhibitor (SSRI) medication, taking action on serotonin levels of a patient with PE. Dapoxetine treatment causes a delayed response in the areas of the brain that cause ejaculation during sexual activity, meaning that it takes longer to reach an orgasm, by boosting the serotonin level in the body (Kendirci et al, 2007).
Because Priligy works quickly, it should be taken 1 to 3 hours before you expect to have sex. It does not need to be taken every day.
How do I take Priligy?
Priligy is a tablet. It should be swallowed whole as this helps to avoid the bitter taste. Taking Priligy with a full glass of water can help to minimise side effects. You can take Priligy with or without food.
What is the proper dosage of Priligy?
Priligy 30mg / 60mg
Priligy tablets are available in two strengths, 30mg and 60mg.
Men should initially take the 30mg dose. If this dose is not high enough, and no severe side effects are experienced, then the dose can be increased to 60mg taken when required. However, increasing the dose can increase the risk of side effects.
Only one Priligy tablet can be taken in a 24 hour period.
What are the side effects of Priligy?
Priligy Side Effects
Like all medications, Priligy can have some side effects that can impact general health. The most common side effects include:
- Dizziness or feeling faint
- Nausea (feeling sick)
Drinking a full glass of water when taking Priligy can help to minimise the side effects. However, if they persist or become troublesome, you should speak to your doctor for further advice.
Feelings of dizziness and/or fainting are more likely if you are taking alpha-blocker medicines for high blood pressure or an enlarged prostate (InformedHealth.org (2018)). If you experience dizziness or feel faint, you must not drive or operate machinery until this side effect subsides.
Serious allergic reactions happen very rarely. If you have a severe allergic reaction (anaphylaxis) including breathlessness, lip swelling or tongue swelling, call 999 immediately.
What warnings does Priligy come with?
Priligy may not be suitable for everyone. You should tell your prescriber if you:
- Have a heart problem like heart failure
- Heart problems such as ischaemic heart disease (a previous heart attack or angina)
- Tend to faint
- Have heart valve disease
- Have an abnormal heart rhythm
- Have a bleeding or clotting disorder
- Have epilepsy
- Have glaucoma
- Have kidney problems / kidney disease
- Have liver disease
- Have a history of mental health issues such as bipolar disorder, mania, serious mood swings, or severe depression
- Have ever had an allergic reaction to a medication.
Your prescriber can then advise whether Priligy is a suitable medication for you.
Certain medicines can interact with Priligy. You may be advised that Priligy will not suit you if you already take:
- Medications for erectile dysfunction
- MAOI (Monoamine Oxidase Inhibitors) and other antidepressants
- Medicine for schizophrenia or other psychiatric disorders
- Triptans for migraine
- St John’s Wort (Hypericum perforatum).
Priligy should not be used in combination with alcohol or recreational drugs.
Can I take erectile dysfunction (ED) medication together with Priligy?
It is not recommended to take Priligy at the same time as erectile dysfunction medications (including PDE5 inhibitors such as sildenafil), as ED medication can cause an adverse event such as low blood pressure. Patients with cardiovascular disease should use all erectile dysfunction drugs (such as a PDE5 inhibitor) with caution (Waller et al, 2018). Tuken et al (2019) found that headaches, palpitations, and flushing were the common adverse effects of dapoxetine/sildenafil combination therapy to treat adult men with premature ejaculation and concomitant erectile dysfunction. You should always consult your doctor, healthcare professional or pharmacist prior to starting Priligy (Dapoxetine), whether or not you suffer from any chronic conditions, to ensure that it is the safest and most suitable premature ejaculation (PE) treatment to suit you - they will check your blood pressure and pulse when sitting down and after standing up before prescribing Priligy, to avoid any issues relating to orthostatic hypotension (Kowey et al, 2011).
What alternative premature ejaculation treatments are available to Priligy?
Whilst Priligy (Dapoxetine) is an effective oral tablet premature ejaculation treatment (McMahon, 2011; McMahon, 2012; Du et al, 2019; Liu et al, 2022), another effective alternative PE treatment is EMLA cream, which comes in a topical cream form and contains the active ingredient combination of lidocaine/prilocaine (Atikeler et al, 2002).
Are there any clinical trials researching daproxetine?
There are various clinical trials and studies researching daproxetine (the active ingredient in Priligy), as a premature ejaculation treatment. Below are some notable research studies:
Can daproxetine cause any cardiovascular adverse events?
Daproxetine (the active ingredient in Priligy), has been associated with vasovagal-mediated (neurocardiogenic) syncope, although no other adverse cardiovascular adverse events we noted in the same study by Kowey et al (2011).
Can daproxetine improve interpersonal difficulty?
Yes, following dapoxetine therapy, patients have reported various improvements such as significantly reduced interpersonal difficulty, greater control over their ejaculation and an overall increase in satisfaction with sexual intercourse (McCarty & Dinsmore, 2012; Kaufman et al, 2008).
Is discontinuation of daproxetine therapy common?
Some studies suggest that patients using SSRI's such as daproxetine may eventually discontinue using it. For example, McMahon, C. (2011), found that 30% of patients (men suffering from lifelong PE) eventually discontinued therapy. Similarly, premature ejaculation patients may discontinue using daproxetine due to the cost and over-reliance on the drug for adequate sexual function (Park et al, 2017).
Can premature ejaculation be cured naturally?
There are natural techniques, such as doubling the number of orgasms a man has each week (DerSarkissian, C., 2022), that can be tried to help to treat premature ejaculation naturally. If these prove unsuccessful you can speak to a doctor or healthcare professional to see if a prescription medication such as Priligy (dapoxetine) could be suitable for your requirements.
What experiences have Priligy users had?
Every patient suffering from a sexual problem such as premature ejaculation has a unique individual experience when taking Priligy as a treatment.
Many users have provided a Priligy review and researchers have studied how effective the active ingredient dapoxetine is. Please refer to Mid-Day.com and Nice.org.uk, alongside McCarty & Dinsmore's (2012) study into the effectiveness of Dapoxetine as a premature ejaculation (PE) treatment.
Where to buy Priligy online?
You can safely buy Priligy online here at EU Meds. Our purchase process will guide you through getting the necessary prescription and receiving your order online through a UK-located pharmacy.
Because Priligy (Dapoxetine) may not suit everyone, we will complete a Consultation with you including a health questionnaire. This will ensure that the medication will be suitable for you.
A qualified prescriber will review your current medications, including any herbal remedies or supplements, to ensure that Priligy will not interact with them.
Once prescribed, Priligy will be ordered on your behalf via electronic prescription. Priligy will then be conveniently dispatched from one of our partner pharmacies. Should you need assistance our customer service team will be happy to help you.
Can I get Priligy at Amazon?
At the time of writing, Priligy is not available at Amazon. However, should you wish to purchase Priligy 30mg tablets or Priligy 60mg tablets, they are available to purchase at EU Meds. Should you wish to buy a larger quantity of Priligy tablets, you can benefit from further savings at EU Meds.
- Drugs.com: History of Priligy
- Drugs.com: International dapoxetine
- WebMD: Overcoming Ejaculation Problems
- NHS UK: Ejaculation Problems
- ScienceDirect: Topics in Medicine and Dentistry - Dapoxetine
- BNF: Dapoxetine
- Patient.info: Dapoxetine Tablets (Priligy)
- NetDoctor: Priligy (Dapoxetine)
- Medicines.org.uk: Priligy Product Information
- Medicines.org.uk: Dapoxetine Product Information
- NICE: Premature Ejaculation: Dapoxetine - Full Evidence Summary
- Drugbank.org: Dapoxetine
- EMA - Priligy