Zopiclone Half-Life: How Long Does Zopiclone Stay In Your System?

    Zopiclone is a commonly prescribed sleeping tablet in the UK that is used to treat short-term insomnia. It helps you fall asleep faster and stay asleep longer. But, how long does it stay in your system? To answer that, we need to understand its half-life. In this article, we will cover the half-life of Zopiclone, as well as how it works, how long you can use it for, and why you should only use it under medical supervision.

    What Is a Drug’s Half-Life?

    The half-life of a drug is the time it takes for half of it to leave your body. Knowing the half-life of a medication like Zopiclone helps explain how long it works, when it wears off and how it may affect you the next day.

    Key Takeaways

    • Zopiclone has a half-life of about 5 hours; however, the effects can last up to 8 hours or more.

    • It’s meant for short-term use only, usually no more than 7 to 10 days.

    • Long-term use can lead to dependence, tolerance and side effects.

    • Factors like your age and liver health can affect how long it stays in your system.

    • Always follow medical advice when using zopiclone.

    How Does Zopiclone Work?

    Zopiclone is a type of medication known as a non-benzodiazepine hypnotic. It works by boosting a calming chemical in the brain called GABA (gamma-aminobutyric acid). This helps you relax and fall asleep.

    It usually starts working within 30 to 60 minutes, and its effects can last for 6 to 8 hours. That’s why it’s suggested that you take it before you go to bed [1].

    The half-life of Zopiclone is about 5 hours, meaning your body clears half the dose in that time [2]. Traces of the medicine can stay in your system for longer, especially in older adults or people with liver or kidney problems. This can cause drowsiness or a metallic taste in the mouth the day after you have used it.

    Is Zopiclone Safe for Long-Term Use?

    No. Zopiclone is not meant to be used as a long-term insomnia treatment. It’s usually prescribed for short periods, no more than 7 to 10 days, to avoid issues like:

    • Tolerance (where it stops working as well)

    • Dependence (your body gets used to it)

    • Withdrawal (anxiety, poor sleep, or other symptoms when you stop)

    Doctors in the UK recommend non-medication options like Cognitive Behavioural Therapy (CBT) as the best long-term treatment for chronic insomnia.

    Why You Should Only Use Zopiclone Under Medical Supervision

    Zopiclone is classified in the UK as a prescription-only medicine. This means you must have a prescription from a medical professional to obtain it. Using it without a doctor’s advice can be unsafe. A healthcare professional can:

    • Properly diagnose your sleep problem

    • Decide if zopiclone is suitable for you and your condition

    • Check for any medication interactions or health risks

    • Monitor side effects and dependency risk

    At PharmXtra, all requests for zopiclone are reviewed after you have completed an online consultation. A registered independent prescriber must approve each request before the medicine can be delivered to you.

    Frequently Asked Questions

    What is the half-life of zopiclone?

    The half-life of zopiclone is around 5 hours, which means your body clears half the dose in that time. It’s important to note that this may take longer for some people, as outlined above.

    Does age affect how long zopiclone stays in your system?

    Yes, older adults or people with reduced liver or kidney function may take longer to process the medicine. This can increase the chances of experiencing side effects.

    Is it safe to take zopiclone long-term?

    No. It’s not meant for long-term use. Prolonged use can lead to dependence, reduced effect and withdrawal symptoms. Always follow your prescriber’s advice.

    Final Thoughts

    Zopiclone can help with short-term sleep problems, but it’s not a cure for chronic insomnia. Understanding how long it stays in your body can help you use it safely and avoid side effects. If you’re unsure about your sleep health or need support, speak to your GP or pharmacist for professional guidance.

    Sources

    [1] How Long for Zopiclone to Work? - PharmXtra

    [2] Zopiclone 7.5mg tablets - NHS

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