How long does co-codamol take to work?

In this article, we'll explain everything you need to know about co-codamol. We'll explain what type of medication it is, how it works and how long it typically takes to start providing relief. We will also answer the question of whether how you use it changes its effectiveness, and how different factors might influence its efficacy.

Key Takeaways

Here are the 5 biggest takeaways from this article about co-codamol and how long it takes to work:

• Co-codamol is a painkiller combining paracetamol and codeine, used to manage moderate pain not relieved by standard painkillers.

• Co-codamol targets pain receptors in the central nervous system and brain to block pain signals.

• Co-codamol typically starts working within 1 hour, with effects lasting around 5 hours.

• The effectiveness and onset of co-codamol can be influenced by how it is used. Taking it with water on an empty stomach ensures better absorption and quicker action.

• Long-term use of co-codamol can lead to tolerance, requiring higher doses for the same pain relief, and potentially increased sensitivity to pain.

What kind of drug is Co-codamol?

Co-codamol is a type of painkiller used to treat moderate pain according to Cancer Research UK. It combines two active ingredients, paracetamol and codeine, an opioid medication that helps to alleviate more intense pain. This combination makes co-codamol effective for managing pain that isn't relieved by standard painkillers alone.

How does Co-codamol work?

Co-codamol works by targeting pain receptors in the central nervous system and the brain, effectively blocking pain signals from reaching the rest of the body (NHS, 2023). The paracetamol in the medications helps to reduce pain and fever, while the codeine blocks pain receptors, providing stronger pain relief. When codeine blocks these receptors it can lead to unwanted side effects such as slow and shallow breathing and slowed digestion.

How long does co-codamol take to work?

According to the NHS, co-codamol typically takes up to 1 hour to start working. Its effects can last for about 5 hours. The most common side effects of co-codaml usage include constipation, nausea and drowsiness.

When will I feel better after taking co-codamol?

As mentioned above, after you have taken co-codamol, you should start to feel relief within 1 hour according to the NHS. This should last for around 5 hours. It is crucial to stick to the recommended dosage of co-codamol to reduce the risk of side effects and to remain safe.

Does how I use Co-codamol affect how long it takes to work?

Yes, how you use co-codamol can affect how long it takes to work. Taking co-codamol with a glass of water and following the recommended usage instructions help to ensure it starts working properly. It's best to take the medication on an empty stomach, as food can delay its absorption. Always follow your healthcare provider's instructions to achieve the best results and minimise potential side effects.

Developing a tolerance with long-term use

With long-term use, your body can develop a tolerance to the codeine in co-codamol. This means you may require higher doses to achieve the same level of pain relief over time. Some people may also experience increased sensitivity to pain, known as hyperalgesia, according to the NHS.

Alcohol and recreational drugs

It's best to avoid alcohol during the first few days of taking co-codamol to see how it affects you, as alcohol can increase drowsiness and the risk of serious side effects. Apart from alcohol, you can eat and drink normally. Using recreational drugs like cannabis, cocaine, or heroin while on co-codamol can significantly increase the risk of severe side effects such as breathing difficulties, heart problems, seizures, and coma. Cannabis can heighten drowsiness and dizziness, and taking heroin with co-codamol is particularly dangerous. This is because it raises the risk of all codeine side effects, including addiction (NHS, 2023).

Does the dosage of co-codamol you take affect how long it takes to work?

No, the dosage of co-codamol you take does not affect how long it takes to start working. Patients should always follow their doctor's instructions regarding when and how much to take. According to Cancer Research UK, adults are usually advised to take 1 or 2 tablets every 4 to 6 hours, with a maximum of 8 tablets in 24 hours. The appropriate dose depends on your pain level and should be prescribed by your healthcare provider. 

Medically Reviewed by:
Dr. Irfan Siddique MBBS
GMC reference no: 7694522
LinkedIn

Sources

Co-codamol for adults: painkiller containing paracetamol and codeine - NHS

Co-codamol (Kapake, Solpadol, Tylex) | Cancer information

Co-Codamol - an overview | ScienceDirect Topics

Co-codamol 30mg/500mg Tablets - Summary of Product Characteristics (SmPC) - (emc)