Is it safe to take Zopiclone with other medications?

In this article, we will explore the safety considerations you need to make when combining Zopiclone with other medications. We will examine the active ingredient in Zopiclone and its potential interactions with various medications, foods, and drinks. Our focus is on providing clear, straightforward information to empower you in making informed decisions about your health.

What is the active ingredient in Zopiclone?

The active ingredient in Zopiclone is, according to the emc, Zopiclone itself. This compound belongs to a class of medications known as non-benzodiazepine hypnotics. Zopiclone acts on the central nervous system, specifically enhancing the effect of a neurotransmitter called gamma-aminobutyric acid (GABA).

Zopiclone is primarily prescribed as a sleep aid for the short-term treatment of insomnia. Its purpose is to help individuals who experience difficulty falling asleep or staying asleep. It's important to note that Zopiclone is typically recommended for short-term use, usually no more than four weeks, to avoid the potential for dependence or tolerance.

Does Zopiclone interact with other medications?

Yes, Zopiclone can interact with certain medications. Here are interactions with some commonly known medications according to the National Institute for Health and Care Excellence:

• Agomelatine: Both Zopiclone and Agomelatine can cause sedation, which might affect the ability to perform skilled tasks.

• Alfentanil: Both Zopiclone and Alfentanil can cause sedation, potentially affecting the ability to perform skilled tasks.

• Alimemazine: Both Zopiclone and Alimemazine can cause sedation, which might impact the ability to perform skilled tasks.

• Alprazolam: Both Zopiclone and Alprazolam can cause sedation, which might affect the ability to perform skilled tasks.

• Amisulpride: Both Zopiclone and Amisulpride can cause sedation, potentially impacting the ability to perform skilled tasks.

It's essential to be cautious when combining these medications, and it's advisable to consult with a healthcare professional to ensure safe usage. Zopiclone can also interact with a number of different medications and can vary in severity of reaction. It is important to speak to your healthcare provider before you begin using any other medications alongside Zopiclone.

What are the typical adverse reactions reported from Zopiclone's interactions with other medications?

The interactions between Zopiclone and certain medications can result in increased sedation and potential side effects. According to the NHS, medications used for schizophrenia, bipolar disorder, depression, epilepsy, anxiety, or sleep problems may intensify the sedative effects of Zopiclone. Additionally, drugs for hay fever, allergies, and strong painkillers can contribute to heightened drowsiness when combined with Zopiclone. Antibiotics like erythromycin or clarithromycin, as well as certain antifungal medications and HIV treatments like ritonavir, may also interact with Zopiclone.

Does Zopiclone interact with alcohol?

Yes, according to the NHS, both Zopiclone and alcohol can have sedative effects on the central nervous system. Combining them may lead to an increased risk of drowsiness, dizziness, and impaired coordination. This interaction can affect your ability to perform tasks that require alertness, such as driving. It is advisable to avoid alcohol while taking Zopiclone or, if necessary, to use alcohol cautiously and under the guidance of a healthcare professional.

Does Zopiclone interact with food?

According to the NHS, Zopiclone can be taken with or without food, as per your doctor's instructions. It's crucial to follow your doctor's guidance on the dosing schedule, as they may recommend taking the tablet on specific nights of the week rather than every night. When taking Zopiclone, ensure to swallow the tablet whole and avoid crushing or chewing it. This medication is designed to help with sleep, and adherence to your doctor's instructions will contribute to its effectiveness. 

Sources

• BNF - Zopiclone interactions

• EMC - Zopiclone PIL

• EMC - Zopiclone Summary of Product Characteristics (SmPC)

• NHS - How and when to take Zopiclone